About Us
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HOME – Laboratory Medicine
The Department of Laboratory Medicine at Basavatarakam Indo American Cancer Hospital and Research Institute is a cost-effective one-stop-shop for diagnosis in oncology without compromising on quality. The Laboratory Medicine department provides services in Haematology, Cytology & Histopathology, Biochemistry, Microbiology and Molecular Pathology. The professional team consists of dedicated specialist doctors trained in respective fields with vast experience in oncology, molecular scientists, technologists/technicians and other support staff. The Labs are accredited by NABL (National Accreditation Board of Laboratories)..
The main aim of the department is to provide high-quality service in the shortest possible time. The department proactively traces all positive reports and shares the findings with the treating consultants for better understanding, which helps to reduce any possible nosocomial infections.
BIACH&RI has advanced chemiluminiscence systems to enable precise quantification of tumour markers and other diagnostic parameters. The department offers a comprehensive range of biochemical tests with strict adherence to quality control protocols.
The Frozen Section facility is made available in the Operation Theatre complex so that a Histopathology report is generated within a few minutes while the patient is still under anesthesia. The Frozen Section enables a surgeon to take an immediate decision to proceed with radical surgery or not, as it firmly establishes malignancy in cases of doubt and also helps in the adequacy of resection, determining whether surgical margins need to be re-excised. Specialized oncopathologists with experience of over 15 years render frozen diagnosis for appropriate cancer management.
A large number of cancer specimens are evaluated by histopathologists with vast experience in a streamlined workflow to render accurate diagnoses at faster turnaround times. CAP reporting formats with adherence to standard guidelines at the time of grossing enable the oncologists and other specialists to make accurate treatment decisions. Access to state-of-the-art liquid-based cytology and efficient cytospin for cytology enables trained cytopathologists to complement the histopathology services.
The institute takes pride in being one of the largest centers handling immunohistochemistry in the state with approximately 12000 IHC markers annually in cancer. Fully automated IHC stainers with a wide panel of antibodies under the supervision of experienced histopathologists enable accurate diagnosis. These consist of various diagnostic and prognostic markers of cancer. Ours is one of the very few centres in the country offering IHC for ALK D5F3 IHC and FISH for EML4/ALK (both under the same roof) for diagnostic dilemmas for lung adenocarcinoma. Immunohistochemistry helps in definite diagnosis in poorly differentiated tumors, lymphomas, and sarcomas, etc. Without a baseline definite diagnosis, any definitive treatment is not possible. This is enabled by availability at a very reasonable tariff and the Institute has been catering to several centres across the state & outside the state for the past 15 years.
The Institute is one of the first centres to start flow cytometry in the state for Stem cell enumeration and leukemia/lymphoma in 2004. Bone marrow aspiration and biopsies are performed on an outpatient basis reported by trained hematopathologists with the help of ancillary techniques like Flow cytometry, FISH & Cytogenetics.
BIACH&RI was the first in the state to initiate FISH in Oncology. Detection of BCR-ABL, PML-RARA /AML 1-ETO / TEL-AML-1/MLL / Inv 16 /De1 13q /Del 11q chromosomal rearrangements in haematological malignancies by Fluorescence in situ Hybridization (FISH) is provided. Assessment of Her-2 /neu gene amplification in breast cancers, EWSR 1 & SYT break apart rearrangement in solid tumours, EML4 –ALK in lung cancers and other markers is also rendered for the diagnosis, prognostication to determine the therapy and follow-up. Karyotyping of blood and bone marrow samples is also offered.
The institute takes pride in being one of the few centres offering Molecular oncology services by RT PCR & Conventional PCR using FDA approved kits. A streamlined approach with pathologists and oncologists actively coordinating with molecular biologists to arrive at an optimum diagnosis and result is vital for patient care in Oncology and that is the strength of Basavatarakam labs in the era of precision medicine. We believe in a multidisciplinary approach to Molecular Oncology. The lab offers EGFR, K ras, N ras, Bcr-abl (Qualitative & Quantitative), HPV etc.
